Virulence-associated 15- to 17-kilodalton antigens in Rhodococcus equi: temperature-dependent expression and location of the antigens
نویسندگان
چکیده
منابع مشابه
Rhodococcus equi: Pathogenesis and Virulence
Inhalation of the facultative intracellular bacterium, Rhodococcus equi, can result in a severe pyogranulomatous pneumonia in young horses and immunocompromised people. This organism is able to resist innate immune defenses and establish residence within the intracellular environment of the alveolar macrophage. Virulence determinants of R. equi have yet to be fully elucidated, but all equine is...
متن کاملRestriction fragment length polymorphisms of virulence plasmids in Rhodococcus equi.
Virulent Rhodococcus equi, which is a well-known cause of pyogranulomatous pneumonia in foals, possesses a large plasmid encoding virulence-associated 15- to 17-kDa antigens. Foal and soil isolates from five countries-Argentina, Australia, Canada, France, and Japan-were investigated for the presence of 15- to 17-kDa antigens by colony blotting, using the monoclonal antibody 10G5, and the gene c...
متن کاملPrevalence of the virulence-associated gene of Rhodococcus equi in isolates from infected foals.
The prevalence of the plasmid-encoded virulence-associated gene (vapA) of Rhodococcus equi, as determined by PCR, was found to be 98% in isolates from 154 foals with pneumonia, confirming the strong association of vapA with virulence. The vapA genes from 60 representative isolates were compared by digestion with the restriction endonuclease HinfI, and no evidence of sequence variation was detec...
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پس ازفروپاشی شوروی،رشد منابع نفت و گاز، آسیای میانه و قفقاز را در یک بازی ژئوپلتیکی انرژی قرار داده است. با در نظر گرفتن این منابع هیدروکربنی، این منطقه به یک میدانجنگ و رقابت تجاری برای بازی های ژئوپلتیکی قدرت های بزرگ جهانی تبدیل شده است. روسیه منطقه را به عنوان حیات خلوت خود تلقی نموده و علاقمند به حفظ حضورش می باشد تا همانند گذشته گاز طبیعی را به وسیله خط لوله مرکزی دریافت و به عنوان یک واس...
15 صفحه اولDevelopment of Hyperimmune Equine Plasma to Virulence Associated Protein A (VapA) of Rhodococcus equi
Procedure – A proprietary formulation of ATCC 33701 Rhodococcus equi known to contain the virulence plasmid was developed and tested on 72 horses. Antibody levels to Rhodococcus equi Virulence associated protein A (VapA) were determined relative to a Standard Plasma. A clinical trial was performed on 28 foals. Seven foals were administered hyperimmune plasma and seven foals were administered pu...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1992
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.60.7.2995-2997.1992